Beta-alanine is an amino acid derivative that has been shown to increase carnosine concentrations within skeletal muscle. Carnosine has been shown to enhance the buffering capacity during high-intensity exercise. Creatine supplementation alone has been shown to reduce fatigue in anaerobic exercise thus beta-alanine supplementation may further reduce the rate of fatigue in muscles.
Hoffman, J. R. et al  examined the effects of creatine and creatine plus beta-alanine on strength, power, body composition, and endocrine changes. Thirty-three male underwent a 10-week resistance training program and were randomly assigned to either a placebo (P – 10.5 g/day of dextrose), creatine (C – 10.5 g/day ), or creatine plus beta-alanine (CA – 10.5 g/day creatine monohydrate and 3.2 g/day of beta-alanine) group. Lean body mass and body fat percentage changes were greater in CA group compared to C or P group. Strength improvements were greater in CA and C groups.
Creatine with beta-alanine appeared to have the greatest effect on lean tissue increase and body fat composition.
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Suzuki, Yasuhiro, et al. “High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting.” The Japanese journal of physiology 52.2 (2002): 199-205.
Hoffman, Jay R., et al. “Effect of low-dose, short-duration creatine supplementation on anaerobic exercise performance.” J Strength Cond Res 19.2 (2005): 260-4.
Hoffman, J. R., et al. “Effect of creatine and ß-Alanine supplementation on performance and endocrine responses in strength/power athletes.” Int. J. Sport Nutr. Exerc. Metab 16 (2006): 430-446.